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Penthrox Inhaler – Methoxyflurane Inhalation Analgesic – Single-Use Pain Relief Device
Penthrox Inhaler is a single-use, handheld inhalation analgesic containing methoxyflurane for the supervised self-administration of pain relief in conscious adults. Designed to help reduce moderate to severe acute pain after injury or during certain medical procedures, it offers a needle-free, non-opioid option that patients can use as needed under the guidance of a healthcare professional.
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In stock
SKU
POM0110
Methoxyflurane Inhalation Device for Acute Pain Relief in Adults
Penthrox Inhaler is a single-use, handheld analgesic device containing methoxyflurane inhalation vapour. Often referred to as the “Green Whistle”, it is used to help reduce the severity of pain in adults following injury or during certain painful procedures, such as dressing changes. It is designed to provide inhaled pain relief without the need for injections, cannulas or more complex set-up.
The device is self-administered under the supervision of a healthcare professional, allowing the user to control when they inhale and how often. Effects are typically felt within a few breaths, and pain relief may continue for several minutes after use stops. Penthrox is intended to reduce pain rather than remove it completely. In the UK, it is licensed for adult use only.
8 Benefits of the Penthrox Inhaler
- Methoxyflurane inhalation analgesic: Penthrox contains methoxyflurane 99.9%, delivered as an inhaled vapour through a handheld single-use device for short-term pain relief in supervised clinical settings.
- Patient-controlled use: The inhaler is self-administered under the supervision of a healthcare professional, allowing the patient to inhale as needed and adjust use according to their level of discomfort.
- Quick to use: The device is simple to prepare and does not require canisters, cannulas or intravenous access, supporting straightforward use in emergency care and during painful procedures.
- Non-opioid option: Penthrox provides a non-opioid form of inhaled analgesia for adults with acute pain following injury or during certain medical procedures.
- Inhaled, non-invasive delivery: As pain relief is delivered by inhalation, it can be used without injections, making it a practical option where a portable, handheld format is preferred.
- Adjustable dosing during use: Patients can inhale continuously or intermittently, and the device design allows the dose to be increased when required, helping tailor use to individual needs.
- May support procedure management: In some care settings, Penthrox may help reduce the need for procedural sedation, depending on the patient, procedure and clinical judgement.
- Adult use in the UK: Penthrox is licensed in the UK for adult use only and is not intended for use in children.
Intended Users and Clinical Environments
Penthrox Inhaler is intended for adult patients in the UK who need short-term inhaled pain relief under the supervision of a healthcare professional. It may be used for people experiencing acute pain following injury or during painful medical procedures, such as dressing changes, where a clinician considers it appropriate.
This product is suited to settings where fast, non-invasive, single-use pain relief is required, including clinical, emergency and pre-hospital environments. Because it is self-administered once set up by a clinician, it may also be suitable where the patient needs to control their own inhalation during use.
Penthrox is designed to reduce the severity of pain rather than remove it completely. In the UK, it is licensed for adults only and is not for use in children.
How to use the Penthrox Inhaler
Penthrox is a self-administered inhalation analgesic for adult use only in the UK and should be used under the supervision of a healthcare professional.
Before use, the inhaler is prepared with the supplied 3 ml bottle of methoxyflurane. The patient then places the mouthpiece between the teeth, seals the lips around it, and inhales through the device as instructed.
Most users begin to notice pain relief after 6 to 10 breaths. The inhaler can then be used continuously or as needed, allowing the patient to control their intake according to their level of discomfort. If stronger analgesia is required, the dilutor hole on the clear chamber can be covered with a finger to increase the concentration inhaled.
Penthrox is intended to reduce the severity of pain, rather than remove it completely. Pain relief may continue for a short time after inhalation stops. The vapour has a characteristic fruity odour and taste, and some users may feel light-headed or drowsy while using it.
A maximum of two 3 ml bottles per administration may be used. Do not exceed this maximum dose.
Product Specifications
| Specification | Details |
| Active Ingredient | Methoxyflurane |
| Quantity per Bottle | 3ml |
| Product Form | Inhalation vapour liquid |
| Device Type | Single-use handheld inhaler with activated carbon (AC) chamber |
| Intended Use | Inhaled analgesic for the reduction of pain severity in adults |
Frequently Asked Questions
Penthrox is a handheld inhalation analgesic used to help reduce pain in adults. It contains methoxyflurane and is commonly known as the “Green Whistle”.
Penthrox is used for short-term relief of acute pain, such as pain following an injury or during certain medical procedures, including dressing changes.
Penthrox contains methoxyflurane, a general inhalation anaesthetic used for analgesia. When inhaled, it helps reduce the body’s response to pain.
Penthrox is intended to reduce the severity of pain, but it may not remove it completely.
Effects are usually felt after around 6 to 10 breaths, with pain relief starting within minutes of inhalation.
Penthrox is self-administered under the supervision of a healthcare professional. The mouthpiece is placed between the teeth, with lips closed around it, and the vapour is inhaled as needed.
Penthrox is a clear, almost colourless volatile liquid before use. When used with the inhaler, it becomes a vapour with a characteristic fruity odour.
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